Steroids after the Kasai procedure for biliary atresia: the effect of age at Kasai portoenterostomy
نویسندگان
چکیده
منابع مشابه
A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia
PURPOSE Kasai portoenterostomy is the standard therapy for biliary atresia (BA). If Kasai is unsuccessful, there is controversy over whether revision of Kasai restores adequate biliary drainage. Although there are several reports of laparoscopic Kasai (Lap-Kasai), none has described laparoscopic revision (Lap-revision). The purposes of this study were to evaluate the feasibility and efficacy of...
متن کاملReview of redo-Kasai portoenterostomy for biliary atresia in the transition to the liver transplantation era
Portoenterostomy (PE) is the standard therapy for biliary atresia (BA). PE offers the chance of survival to children with BA. PE was the ultimate therapeutic modality for BA before liver transplantation (LT) was available. Failure of biliary drainage with PE was almost invariably fatal in children with BA. In such cases, redo-PE was performed to salvage patients following PE failure. PE remains...
متن کاملBiliary Atresia: 50 Years after the First Kasai
Biliary atresia is a rare neonatal disease of unknown etiology, where obstruction of the biliary tree causes severe cholestasis, leading to biliary cirrhosis and death in the first years of life, if the condition is left untreated. Biliary atresia is the most frequent surgical cause of cholestatic jaundice in neonates and should be evoked whenever this clinical sign is associated with pale stoo...
متن کاملMaximizing Kasai portoenterostomy in the treatment of biliary atresia: medical and surgical options.
Biliary atresia (BA) remains one of the most challenging conditions in paediatric surgery. It has several possible causes, resulting in a range of different clinical scenarios. The current therapeutic approach is almost entirely surgical with an initial attempt to restore bile flow and preserve the native liver using a Kasai-type portoenterostomy. Liver transplantation (cadaveric or living dono...
متن کاملHigh-dose steroids, ursodeoxycholic acid, and chronic intravenous antibiotics improve bile flow after Kasai procedure in infants with biliary atresia.
BACKGROUND/PURPOSE Early reports suggest that the use of steroids after Kasai portoenterostomy may improve bile flow and outcome in infants with biliary atresia. METHODS Of 28 infants with biliary atresia, half received adjuvant high-dose steroids, and half received standard therapy. Infants in the steroid group (n = 14) received intravenous solumedrol (taper of 10, 8, 6, 5, 4, 3, 2 mg/kg/d),...
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ژورنال
عنوان ژورنال: Pediatric Surgery International
سال: 2015
ISSN: 0179-0358,1437-9813
DOI: 10.1007/s00383-015-3836-3